objective(s): bone marrow mesenchymal stem cells (mscs) play an important role in bone health. cadmium causes osteoporosis, but the exact mechanisms of its effect on mscs are not known. materials and methods: rats were treated with cadmium chloride (40 mg/l) in drinking water for six weeks, and then the biochemical and morphological studies on mscs were carried out as a cellular backup for oste...

â  â  background non-alcoholic fatty liver disease/steatohepatitis (nafld/nash) is the most common form of chronic liver disease woldwide and is no longer considered a benign disease. its prevalence has not been deterâ­mined in a large-scale population-based study in iran. me t hod s a total of 6583 individuals aged 18 to 65 were randomly selected from three geographically distinct provinces in...

conclusions considering the significant decrease in the liver enzymes, triglycerides and cholesterol after using berberis vulgaris extract, further studies with larger sample sizes will identify the accurate dose as well as duration of consumption for this extract, to recommend in the treatment of patients with nafld. results in the case group, the mean serum levels of alanine transaminase (alt...

background the occult hepatitis b infection (obi) is defined as the presence of hepatitis b virus (hbv) dna in the sera or in the liver biopsy and the absence of hepatitis b surface antigen (hbsag) by serological test. objectives the current study aimed to evaluate the occult hbv infection by polymerase chain reaction (pcr) and determine hbv genotyping among the patients with abnormal alanine t...

objectives: hyperlipidemia can cause a variety of diseases such as atherosclerosis, diabetes, and fatty liver which is followed by increased liver enzymes. since berberis vulgaris (b. vulgaris) root possesses antioxidant properties, the present study was conducted to investigate the effect ofits extract on the activity of liver enzymes in rats. materials and methods: in this experimental study,...

To facilitate molecular analyses of a previously uncharacterized gene involved in alanine synthesis, attempts were made to clone the wild-type allele of this gene, alaA, with a mini-Mu plasmid element used for in vivo cloning. Seventy-six independent Ala+ plasmids were isolated and characterized. Physiological, enzymological, and restriction endonuclease analyses indicated that three different ...

BACKGROUND Severe anoxic brain injury can lead to prolonged episodes of status dystonicus. Sustained dystonia can result in skeletal muscle breakdown and elevation of serum transaminases, which can initially be confused with polypharmacy-related hepatotoxicity or an underlying metabolic condition. PATIENT We present a 19-month-old boy who sustained a severe anoxic brain injury in the setting ...